What is "DNA Sequencing" ?

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Learning -> Resources Available, All Work is Subject to DHRF's "GD"

1 Important Note

“Whole genome sequencing (WGS), also known as full genome sequencing, complete genome sequencing, or entire genome sequencing, is the process of determining the entirety, or nearly the entirety, of the DNA sequence of an organism’s genome at a single time. This entails sequencing all of an organism’s chromosomal DNA as well as DNA contained in the mitochondria and, for plants, in the chloroplast […] Whole genome sequencing has largely been used as a research tool, but was being introduced to clinics in 2014”   Source:   Wikipedia

Image#1 This is based upon a Wikipedia Image

Image#2 (Husband 2023) This is an equivalent “sample” unstructured binary symbol stream which gives no clue as to which domain it exists in… Time domain ? Memory domain ? (as no extra indexes) or any clue about its granularity

(1) The Start of the Binary Symbol Stream

This symbol stream is one long stream until point(2). For display convenience purposes, it “wraps around” 2 at the end of the line on the right hand side, and then continues on the next new line on the left hand side

(2) The End of the Binary Symbol Stream

Research Work Stream RWS-18 discusses unstructured and structured data streams…

1m13   The Age of Big Data    BBC Horizon 2013 3

     Right-Click on the video image to display a number of options… 4

What this approach is equivalent to…

… is taking the most powerful, most complex supercomputer on earth and doing a “binary dump” of its internal software as one long Symbol stream (as in Image#2 above) - (without any idea of its Granularity,or any “indexing” or its Tokens and Meta-Tokens) from just that and attempting to work out what is going on… This is not a good way of proceeding !! 5

References:

Husband, D., 2023. eZ80 SoC FIG-Forth Development System.

Baseline: dna_md_R01;B01

  1. In view of DHRF’s commitment to support learning, there is a much higher “learning content” in the Research Work Streams than would otherwise be the case… Please be aware of that 

  2. In a similar but much simpler manner to how DNA is “coiled and folded up” in the cell… 

  3. The video Clip is used under the “Fair Use Rules” of English Copyright law… 

  4. This is using the in-built video and audio players of HTML5 

  5. But the only way of proceeding for very clever Molecular Biologists who are very focussed upon Implementation Detail (at the molecular level) whereas DHRF/DH is focussing upon “functionality”… See Ignore Implementation Details and Distil Functionality from Implementation Detail 


•  Updated: 16th May 2023 by David Husband  •  Created: 8th May 2023 by David Husband  •
Reviewed: t.b.d. by t.b.d.  •  Status: Awaiting Review
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